Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.89 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.89 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 9/20 | 0.45 |
| ▸ | F10 | P00742 | 9/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8882867 | 1.00 | AKR1C3 (0.89) | AKR1C3AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3438303 | 0.98 | AKR1C3 (0.93) | AKR1C3AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3438304 | 0.98 | AKR1C3 (0.93) | AKR1C3AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9584524 | 0.98 | AKR1C3 (0.93) | AKR1C3AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL625345 | 0.94 | AKR1C3 (1.00) | AKR1C3AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21612350 | 0.94 | AKR1C3 (1.00) | AKR1C3AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1524671 | 0.94 | AKR1C3 (1.00) | AKR1C3AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8886352 | 0.85 | AKR1C3 (0.81) | AKR1C3AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14034063 | 0.85 | AKR1C3 (0.65) | AKR1C3AKR1C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14033871 | 0.85 | AKR1C3 (0.65) | AKR1C3AKR1C1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639918-A | Intermediate compounds useful in the preparation of fungicidal compositions containing (benzylidene)-azolylmethyclycloalkane | RHONE-POULENC AGROCHIMIE (FR) | 1997-06-17 | — | — | US | disclosed |
| CN-1031971-C | (Benzylidene)-azolylmethylcycloalkane and use as fungicide | RHONE POULENC AGROCHIMIE (FR) | 1996-06-12 | — | — | CN | disclosed |
| EP-0378953-B1 | Benzylidene azolyl methyl cycloalkane and its use as a fungicide | RHONE POULENC AGROCHIMIE (FR) | 1996-06-05 | — | — | EP | disclosed |
| US-5380743-A | Fungicidal compositions containing (benzylidene)-azolymethylcycloalkane | RHONE-POULENC AGROCHIMIE (FR) | 1995-01-10 | — | — | US | disclosed |
| US-5256683-A | Plant protective agent 1H-1,2,4-triazolylmethylcycloalkane or -alkene benzylidene | RHONE-POULENC AGROCHIMIE (FR) | 1993-10-26 | — | — | US | disclosed |
| EP-0378953-A1 | Benzylidene azolyl methyl cycloalkane and its use as a fungicide | RHONE-POULENC AGROCHIMIE (FR) | 1990-07-25 | — | — | EP | disclosed |