Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.81 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21612350 | 0.90 | AKR1C3 (1.00) | AKR1C3AKR1C1ALDH1A1HTTEGFR | |
| SCHEMBL1524671 | 0.90 | AKR1C3 (1.00) | AKR1C3AKR1C1ALDH1A1HTTEGFR | |
| SCHEMBL625345 | 0.90 | AKR1C3 (1.00) | AKR1C3AKR1C1ALDH1A1HTTEGFR | |
| SCHEMBL9584524 | 0.87 | AKR1C3 (0.93) | AKR1C3AKR1C1ALDH1A1HTTEGFR | |
| SCHEMBL3438303 | 0.87 | AKR1C3 (0.93) | AKR1C3AKR1C1ALDH1A1HTTEGFR | |
| SCHEMBL3438304 | 0.87 | AKR1C3 (0.93) | AKR1C3AKR1C1ALDH1A1HTTEGFR | |
| SCHEMBL8882867 | 0.85 | AKR1C3 (0.89) | AKR1C3AKR1C1ALDH1A1HTTEGFR | |
| SCHEMBL8882874 | 0.85 | AKR1C3 (0.89) | AKR1C3AKR1C1ALDH1A1HTTEGFR | |
| SCHEMBL3438448 | 0.83 | ALDH1A1 (0.67) | AKR1C3AKR1C1ALDH1A1HTTEGFR | |
| SCHEMBL3438446 | 0.83 | ALDH1A1 (0.67) | AKR1C3AKR1C1ALDH1A1HTTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639918-A | Intermediate compounds useful in the preparation of fungicidal compositions containing (benzylidene)-azolylmethyclycloalkane | RHONE-POULENC AGROCHIMIE (FR) | 1997-06-17 | — | — | US | disclosed |
| EP-0378953-B1 | Benzylidene azolyl methyl cycloalkane and its use as a fungicide | RHONE POULENC AGROCHIMIE (FR) | 1996-06-05 | — | — | EP | disclosed |
| US-5380743-A | Fungicidal compositions containing (benzylidene)-azolymethylcycloalkane | RHONE-POULENC AGROCHIMIE (FR) | 1995-01-10 | — | — | US | disclosed |
| US-5256683-A | Plant protective agent 1H-1,2,4-triazolylmethylcycloalkane or -alkene benzylidene | RHONE-POULENC AGROCHIMIE (FR) | 1993-10-26 | — | — | US | disclosed |
| EP-0378953-A1 | Benzylidene azolyl methyl cycloalkane and its use as a fungicide | RHONE-POULENC AGROCHIMIE (FR) | 1990-07-25 | — | — | EP | disclosed |