Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8882714 | 0.93 | RARB (0.46) | RARBS1PR1S1PR3PTPN11MEN1 | |
| SCHEMBL8882450 | 0.85 | RARB (0.46) | RARBS1PR1S1PR3PLA2G4ARARA | |
| SCHEMBL8885615 | 0.85 | RARB (0.48) | RARBMEN1USP2ALDH1A1KMT2A | |
| SCHEMBL8769198 | 0.84 | RAB9A (0.51) | S1PR1S1PR3MEN1USP2ALDH1A1 | |
| SCHEMBL8884758 | 0.84 | RAB9A (0.51) | S1PR1S1PR3MEN1USP2ALDH1A1 | |
| SCHEMBL17445757 | 0.84 | RARB (0.63) | RARBS1PR1S1PR3PTPN11MEN1 | |
| SCHEMBL8885096 | 0.83 | RAB9A (0.43) | S1PR1S1PR3PTPN11MEN1USP2 | |
| SCHEMBL8885499 | 0.83 | RAB9A (0.43) | S1PR1S1PR3PTPN11MEN1USP2 | |
| SCHEMBL16187781 | 0.81 | RARB (0.52) | RARBS1PR1S1PR3PTPN11MEN1 | |
| SCHEMBL8984168 | 0.81 | RARB (0.52) | RARBS1PR1S1PR3PTPN11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5595685-A | THIAZOLE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 1997-01-21 | — | — | US | disclosed |
| EP-0439170-B1 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KK (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0439170-A2 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KABUSHIKI KAISHA (JP) | 1991-07-31 | — | — | EP | disclosed |