Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883434 | 0.92 | RARB (0.47) | RARBRAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL8882933 | 0.85 | RARB (0.47) | RARBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL8884801 | 0.83 | KDM4E (0.59) | RARBRAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL8769157 | 0.83 | KDM4E (0.59) | RARBRAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL8545371 | 0.83 | KDM4E (0.59) | RARBRAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL8883008 | 0.82 | RARB (0.47) | RARBRAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL8882450 | 0.81 | RARB (0.46) | RARBRARARARG | |
| SCHEMBL8883767 | 0.81 | HSD17B1 (0.51) | RAB9AMAPTSMN1; SMN2NPC1STAT3 | |
| SCHEMBL24599245 | 0.81 | RARB (0.57) | RARBRAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL8984207 | 0.81 | RARB (0.54) | RARBRAB9AMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5595685-A | THIAZOLE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 1997-01-21 | — | — | US | disclosed |
| EP-0439170-B1 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KK (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0439170-A2 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KABUSHIKI KAISHA (JP) | 1991-07-31 | — | — | EP | disclosed |