SCHEMBL888345

SCHEMBL888345

O=C(N[C@@H](CSCC(O)CO)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC17A5 Q9NRA2 1/20 0.56
MDM4 O15151 3/20 0.53
TP53 P04637 3/20 0.53
CASP3 P42574 2/20 0.48
TLR2 O60603 2/20 0.47
MDM2 Q00987 5/20 0.47
KMT2A Q03164 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14765263 1.00 SLC17A5 (0.56) SLC17A5MDM4TP53CASP3TLR2
SCHEMBL2419146 1.00 SLC17A5 (0.56) SLC17A5MDM4TP53CASP3TLR2
SCHEMBL19888241 0.90 SLC17A5 (0.58) SLC17A5MDM4TP53CASP3TLR2
SCHEMBL161752 0.87 MDM4 (0.47) SLC17A5MDM4TP53CASP3MDM2
SCHEMBL161749 0.87 MDM4 (0.47) SLC17A5MDM4TP53CASP3MDM2
SCHEMBL161751 0.87 MDM4 (0.47) SLC17A5MDM4TP53CASP3MDM2
SCHEMBL161750 0.87 MDM4 (0.47) SLC17A5MDM4TP53CASP3MDM2
SCHEMBL14765032 0.87 MDM4 (0.47) SLC17A5MDM4TP53CASP3MDM2
SCHEMBL29386847 0.86 SLC17A5 (0.44) SLC17A5MDM4TP53CASP3KMT2A
SCHEMBL1486194 0.86 SLC17A5 (0.58) SLC17A5MDM4TP53CASP3TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3728289-B1 OPTIMISED COMPOUNDS Axelia Oncology Pty Ltd (AU) 2025-09-10 EP disclosed
US-20250066416-A1 OPTIMISED COMPOUNDS THE UNIVERSITY OF MELBOURNE (AU) 2025-02-27 US disclosed
US-12195557-B2 Optimised compounds Axelia Oncology Pty Ltd (AU) 2025-01-14 US disclosed
CN-118161614-A Treatment of respiratory tract infections with TLR2 agonists 艾娜呼吸私人有限公司 2024-06-11 CN disclosed
EP-3600374-B1 TREATMENT OF RESPIRATORY INFECTION Ena Respiratory Pty Ltd (AU) 2024-05-15 EP disclosed
CN-110461351-B Treatment of respiratory tract infections with TLR2 agonists 艾娜呼吸私人有限公司 2024-03-26 CN disclosed
US-20210230217-A1 OPTIMISED COMPOUNDS Axelia Oncology Pty Ltd (AU) 2021-07-29 US disclosed
US-20210177795-A1 ADMINISTERING COMPOUNDS Axelia Oncology Pty Ltd (AU) 2021-06-17 US disclosed
EP-3728289-A1 OPTIMISED COMPOUNDS Ena Therapeutics Pty Ltd (AU) 2020-10-28 EP disclosed
EP-3727372-A1 ADMINISTRATION OF A TLR2 AGONIST FOR THE TREATMENT OR PREVENTION OF A RESPIRATORY CONDITION ASSOCIATED WITH AN INFECTIOUS AGENT Ena Therapeutics Pty Ltd (AU) 2020-10-28 EP disclosed
EP-1546206-A4 NOVEL IMMUNOGENIC LIPOPEPTIDES COMPRISING T-HELPER AND CYTOTOXIC T LYMPHOCYTE (CTL) EPITOPES QUEENSLAND INST MED RES (AU) 2007-10-10 EP disclosed
EP-1543039-A4 NOVEL IMMUNOGENIC LIPOPEPTIDES COMPRISING T-HELPER AND B-CELL EPITOPES QUEENSLAND INST MED RES (AU) 2007-09-19 EP disclosed
US-20070160631-A1 Novel immunogenic lipopeptides comprising t-helper and cytotoxic t lymphocyte (ctl) epitopes THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH (AU) 2007-07-12 US disclosed
US-20070066534-A1 Novel immunogenic lipopeptides comprising t-helper and b-cell epitopes THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH (AU) 2007-03-22 US disclosed
WO-2006084319-A1 IMMUNOGENIC MOLECULES THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH (AU) 2006-08-17 WO disclosed
WO-2006021048-A1 IMMUNOTHERAPY OF VIRUS INFECTION THE MACFARLANE BURNET INSTITUTE FOR MEDICAL RESEARCH AND PUBLIC HEALTH LIMITED (AU) 2006-03-02 WO disclosed
EP-1546206-A1 NOVEL IMMUNOGENIC LIPOPEPTIDES COMPRISING T-HELPER AND CYTOTOXIC T LYMPHOCYTE (CTL) EPITOPES THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH (AU) 2005-06-29 EP disclosed
EP-1543039-A1 NOVEL IMMUNOGENIC LIPOPEPTIDES COMPRISING T-HELPER AND B-CELL EPITOPES THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH (AU) 2005-06-22 EP disclosed
WO-2004014957-A1 NOVEL IMMUNOGENIC LIPOPEPTIDES COMPRISING T-HELPER AND CYTOTOXIC T LYMPHOCYTE (CTL) EPITOPES THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH (AU) 2004-02-19 WO disclosed
WO-2004014956-A1 NOVEL IMMUNOGENIC LIPOPEPTIDES COMPRISING T-HELPER AND B-CELL EPITOPES THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH (AU) 2004-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070160631-A1 Novel immunogenic lipopeptides comprising t-helper and cytotoxic t lymphocyte (ctl) epitopes LY96, LTA, CD4 SLC17A5 1730/4885MDM4 2025/4885TP53 113/4885
US-20210230217-A1 OPTIMISED COMPOUNDS TLR2, TLR3, TLR1 SLC17A5 1409/4885MDM4 4271/4885TP53 2503/4885
US-20250066416-A1 OPTIMISED COMPOUNDS TLR2, TLR3, TLR1 SLC17A5 1409/4885MDM4 4271/4885TP53 2503/4885
US-12195557-B2 Optimised compounds TLR2, TLR3, TLR1 SLC17A5 1409/4885MDM4 4271/4885TP53 2503/4885
US-20070066534-A1 Novel immunogenic lipopeptides comprising t-helper and b-cell epitopes CD4, LY96, CD69 SLC17A5 1242/4885MDM4 4033/4885TP53 819/4885
US-20210177795-A1 ADMINISTERING COMPOUNDS TLR2, TLR3, TLR5 SLC17A5 400/4885MDM4 3602/4885TP53 3402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.