SCHEMBL888349

SCHEMBL888349

CCOC(=O)CC(C)OC(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
LMNA P02545 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
POLB P06746 1/20 0.48
SCN1A P35498 1/20 0.48
SCN2A Q99250 1/20 0.48
SCN3A Q9NY46 1/20 0.48
TSHR P16473 3/20 0.48
ALDH1A1 P00352 2/20 0.48
TP53 P04637 1/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
GAA P10253 1/20 0.46
RAB9A P51151 1/20 0.46
PDCD1 Q15116 1/20 0.45
CD274 Q9NZQ7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888507 0.86 ALDH1A1 (0.50) NPC1LMNACYP1A2CYP2D6POLB
SCHEMBL28278500 0.85 TSHR (0.52) MEN1KMT2ALMNACYP1A2CYP2D6
SCHEMBL10476848 0.85 LMNA (0.61) NPC1LMNACYP1A2CYP2D6SCN1A
SCHEMBL5080019 0.85 KMT2A (0.58) NPC1KMT2ALMNACYP1A2CYP2D6
SCHEMBL28279379 0.85 LMNA (0.46) NPC1MEN1KMT2ALMNACYP1A2
SCHEMBL5085889 0.85 KMT2A (0.58) NPC1KMT2ALMNACYP1A2CYP2D6
SCHEMBL28279377 0.84 TDP1 (0.51) NPC1MEN1KMT2ALMNAPOLB
SCHEMBL29302944 0.84 LMNA (0.54) NPC1MEN1KMT2ALMNACYP1A2
SCHEMBL5082911 0.84 LMNA (0.54) NPC1MEN1KMT2ALMNACYP1A2
SCHEMBL5082895 0.84 PDCD1 (0.56) NPC1MEN1KMT2ALMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN claimed
CN-109553705-A A kind of catalytic component and preparation method thereof for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN claimed
CN-109553712-A A kind of catalytic component and its catalyst for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN claimed
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed
CN-109553705-A A kind of catalytic component and preparation method thereof for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN disclosed
CN-109553712-A A kind of catalytic component and its catalyst for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN disclosed
EP-2374821-B1 MANUFACTURING METHOD OF SOLID CATALYST COMPONENT AND OF CATALYST FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2015-05-06 EP disclosed
EP-1746110-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2015-03-11 EP disclosed
CN-102272170-B Solid catalyst component for olefin polymerization, manufacturing method, and catalyst and olefin polymer manufacturing method TOHO TITANIUM CO LTD 2014-06-18 CN disclosed
US-8546290-B2 Solid catalyst component for olefin polymerization, manufacturing method, and catalyst and olefin polymer manufacturing method TOHO TITANIUM CO., LTD. (JP) 2013-10-01 US disclosed
CN-100348624-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2007-11-14 CN disclosed
EP-1746110-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF China Petroleum & Chemical Corporation (CN) 2007-01-24 EP disclosed
CN-1891722-A Method for preparing catalyst constituent for olefinic polymerization CHINA PETROCHEMICAL CO LTD (CN) 2007-01-10 CN disclosed
US-20060287446-A1 Catalyst component for olefin polymerization and catalyst comprising the same BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CHINA PETROLEUM & CHEMICAL COPORATION (CN) 2006-12-21 US disclosed
CN-1282670-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-11-01 CN disclosed
CN-1803863-A Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-07-19 CN disclosed
CN-1803862-A Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-07-19 CN disclosed
CN-1690090-A Catalyst components for olefinic polyreaction and catalyst thereof SINOPEC CORP (CN) 2005-11-02 CN disclosed