⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29154803 | 1.00 | — | — | |
| SCHEMBL7621371 | 0.91 | — | — | |
| SCHEMBL7618573 | 0.88 | — | — | |
| SCHEMBL9364312 | 0.80 | — | — | |
| SCHEMBL847026 | 0.80 | — | — | |
| SCHEMBL317886 | 0.79 | — | — | |
| SCHEMBL1012485 | 0.79 | OPRM1 (0.75) | — | |
| SCHEMBL14654820 | 0.79 | — | — | |
| SCHEMBL7734724 | 0.76 | OPRM1 (0.71) | — | |
| SCHEMBL49007 | 0.76 | OPRM1 (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281296-A1 | PROCESS FOR THE PRODUCTION OF CONJUGATES FROM POLYSACCHARIDES AND POLYNUCELOTIDES | SUPRAMOL PARENTERAL COLLOID GMBH (DE) | 2009-11-12 | — | — | US | claimed |
| CN-113166759-B | Chemically modified RNAi constructs and uses thereof | 美国安进公司 | 2024-07-12 | — | — | CN | disclosed |
| US-20240191240-A1 | DEFINED MULTI-CONJUGATES OLIGONUCLEOTIDES | MPEG LA L L C (US) | 2024-06-13 | — | — | US | disclosed |
| US-20240084301-A1 | RNAI CONSTRUCTS AND METHODS FOR INHIBITING FAM13A EXPRESSION | AMGEN INC. (US) | 2024-03-14 | — | — | US | disclosed |
| WO-2024026258-A2 | RNAI CONSTRUCTS AND METHODS FOR INHIBITING FAM13A EXPRESSION | AMGEN INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| US-20240011108-A1 | MASS SPECTROMETRY-BASED METHODS AND KITS FOR NUCLEIC ACID DETECTION AND DISEASE DIAGNOSTIC | YYZ PHARMATECH INC. (CA) | 2024-01-11 | — | — | US | disclosed |
| US-11767531-B2 | Defined multi-conjugates oligonucleotides | MPEG LA, LLC (US) | 2023-09-26 | — | — | US | disclosed |
| US-20230287413-A1 | TARGETED DELIVERY OF AN INHIBITOR OF MIR-21 TO MACROPHAGES FOR THE TREATMENT OF PULMONARY FIBROSIS | Technische Universität München (DE) | 2023-09-14 | — | — | US | disclosed |
| US-20230287406-A1 | MULTIMERIC OLIGONUCLEOTIDES WITH ENHANCED BIOACTIVITY | MPEG LA, L.L.C. | 2023-09-14 | — | — | US | disclosed |
| US-20230278968-A1 | OXAZINE DYES AND THEIR USE IN NUCLEIC ACID AMPLIFICATION REACTIONS | PROMEGA CORPORATION | 2023-09-07 | — | — | US | disclosed |
| WO-1994013325-A2 | PEPTIDE LINKERS FOR IMPROVED OLIGONUCLEOTIDE DELIVERY | MICROPROBE CORPORATION (US) | 1994-06-23 | — | — | WO | disclosed |
| WO-1994002500-A1 | OLIGONUCLEOTIDE PROBES AND PRIMERS FOR DETECTING CHROMOSOMAL TRANSLOCATION | APROGENEX, INC. (US) | 1994-02-03 | — | — | WO | disclosed |
| WO-1994002643-A1 | NUCLEIC ACID PROBES AND USES THEREOF TO DETECT DOUBLE-STRANDED NUCLEIC ACIDS | APROGENEX, INC. (US) | 1994-02-03 | — | — | WO | disclosed |
| WO-1994002645-A1 | RAPID DETECTION OF BIOPOLYMERS IN STAINED SPECIMENS | APROGENEX, INC. (US) | 1994-02-03 | — | — | WO | disclosed |
| WO-1994002644-A1 | IN SITU DETECTION OF NUCLEIC ACIDS USING 3SR AMPLIFICATION | APROGENEX, INC. (US) | 1994-02-03 | — | — | WO | disclosed |
| WO-1994002646-A1 | ENRICHING AND IDENTYFYING FETAL CELLS IN MATERNAL BLOOD FOR IN SITU HYBRIDIZATION | APROGENEX INC. (US) | 1994-02-03 | — | — | WO | disclosed |
| WO-1994000600-A1 | SOLID SUPPORTS FOR NUCLEIC ACID HYBRIDIZATION ASSAYS | MICROPROBE CORPORATION (US) | 1994-01-06 | — | — | WO | disclosed |
| WO-1992018649-A1 | COMPOSITIONS AND METHODS FOR IMPROVED EXTRACTION AND HYBRIDIZATION OF NUCLEIC ACID | MICROPROBE CORPORATION (US) | 1992-10-29 | — | — | WO | disclosed |
| EP-0455905-A2 | Solid supports for nucleic acid hybridization assays and methods for covalently immobilizing oligonucleotides | MICROPROBE CORPORATION (US) | 1991-11-13 | — | — | EP | disclosed |
| US-4206117-A | Pyridinyl aminoalkyl ethers | BASF AKTIENGESELLSCHAFT (DE) | 1980-06-03 | — | — | US | disclosed |