Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | IL1RN | P18510 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23555173 | 0.79 | KMT2A (0.56) | KMT2ACA1CA2HPGDPGR | |
| SCHEMBL2912639 | 0.78 | CA2 (0.51) | KMT2ACA1CA2HPGDCA12 | |
| SCHEMBL633995 | 0.75 | KMT2A (0.76) | KMT2ACA1CA2HPGDPGR | |
| SCHEMBL7938423 | 0.74 | HSPA5 (0.54) | KMT2ACA1CA2HPGDAKR1B1 | |
| SCHEMBL4712987 | 0.72 | HSPA5 (0.52) | CA1CA2AKR1B1HIF1ACA12 | |
| SCHEMBL1245772 | 0.72 | HSPA5 (0.52) | CA1CA2AKR1B1HIF1ACA12 | |
| SCHEMBL29432666 | 0.72 | HSPA5 (0.52) | CA1CA2AKR1B1HIF1ACA12 | |
| SCHEMBL6533144 | 0.72 | CA1 (0.56) | KMT2ACA1CA2HPGDPGR | |
| SCHEMBL15672897 | 0.72 | CA2 (0.56) | KMT2ACA1CA2HPGDPGR | |
| SCHEMBL6567551 | 0.71 | KMT2A (0.70) | KMT2ACA1CA2HPGDPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614536-A | Substituted N-aminoalkylmethane sulfanilide as antispasmodica | ROEMMERS S.A.I.C.F. (AR) | 1997-03-25 | — | — | US | disclosed |