SCHEMBL888388

SCHEMBL888388

CCOC(=O)C(COC)(C(C)C)C(C)(C)CC

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.38
CYP4F2 P78329 3/20 0.33
CYP4A11 Q02928 3/20 0.33
PKM P14618 3/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ABCB11 O95342 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
HTR2A P28223 1/20 0.30
PMP22 Q01453 1/20 0.30
PPARA Q07869 1/20 0.30
ALDH1A1 P00352 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888356 0.87 MMP8 (0.38) MMP8CYP4F2CYP4A11PKMKDM4E
SCHEMBL888586 0.86 MMP8 (0.40) MMP8CYP4F2CYP4A11PKMKDM4E
SCHEMBL888554 0.86 DGAT1 (0.34) MMP8
SCHEMBL819556 0.79
SCHEMBL1785388 0.78 MMP8 (0.43) MMP8CYP4F2CYP4A11PKMKDM4E
SCHEMBL888359 0.74 MMP8 (0.46) MMP8CYP4F2CYP4A11PKM
SCHEMBL8161089 0.74 MMP8 (0.38) MMP8CYP4F2CYP4A11PKMKDM4E
SCHEMBL819839 0.73 MMP8 (0.40) MMP8CYP4F2CYP4A11PKMKDM4E
SCHEMBL14891578 0.73 MMP8 (0.40) MMP8CYP4F2CYP4A11PKMKDM4E
SCHEMBL888471 0.72 MMP8 (0.40) MMP8CYP4F2CYP4A11PKMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed