⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3401100 | 0.82 | — | — | |
| SCHEMBL8376357 | 0.72 | — | — | |
| SCHEMBL8773237 | 0.69 | — | — | |
| SCHEMBL10361273 | 0.69 | — | — | |
| Ethane SCHEMBL29109509 | 0.59 | — | — | |
| Fluoromethane SCHEMBL6246388 | 0.59 | — | — | |
| SCHEMBL14722063 | 0.58 | — | — | |
| SCHEMBL29859818 | 0.58 | — | — | |
| SCHEMBL5048850 | 0.58 | — | — | |
| SCHEMBL1357 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637595-A | PLATELET ACTIVATING FACTOR | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1997-06-10 | — | — | US | disclosed |
| US-5428168-A | Substituted butyrolactol ether derivative | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-06-27 | — | — | US | disclosed |
| EP-0593537-A1 | CYCLIC ETHER ACETAL PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993001191-A1 | CYCLIC ETHER ACETAL PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |