Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400936 | 0.85 | THRA (0.59) | THRASMPD1TP53TSHRPLA2G4B | |
| SCHEMBL10840940 | 0.82 | SMPD1 (0.73) | THRASMPD1TP53TSHR | |
| SCHEMBL10839811 | 0.82 | SMPD1 (0.73) | THRASMPD1TP53TSHR | |
| SCHEMBL10839296 | 0.82 | SMPD1 (0.73) | THRASMPD1TP53TSHR | |
| SCHEMBL10840947 | 0.82 | SMPD1 (0.73) | THRASMPD1TP53TSHR | |
| SCHEMBL9205365 | 0.82 | THRA (0.59) | THRASMPD1 | |
| SCHEMBL5388136 | 0.79 | TP53 (0.77) | THRATP53TSHRPLA2G4B | |
| SCHEMBL14672324 | 0.79 | TP53 (0.77) | THRATP53TSHRPLA2G4B | |
| SCHEMBL5383674 | 0.79 | TP53 (0.77) | THRATP53TSHRPLA2G4B | |
| SCHEMBL9779326 | 0.79 | TP53 (0.77) | THRATP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5595685-A | THIAZOLE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 1997-01-21 | — | — | US | disclosed |
| EP-0439170-B1 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KK (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0439170-A2 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KABUSHIKI KAISHA (JP) | 1991-07-31 | — | — | EP | disclosed |