Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 9/20 | 0.63 |
| ▸ | RARB | P10826 | 9/20 | 0.63 |
| ▸ | RARG | P13631 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771715 | 0.90 | RARA (0.77) | RARARARBRARGALDH1A1MEN1 | |
| SCHEMBL27462421 | 0.81 | RARA (0.72) | RARARARBRARGRAB9ASMN1; SMN2 | |
| SCHEMBL8771659 | 0.80 | RARA (0.59) | RARARARBRARG | |
| SCHEMBL8981568 | 0.79 | RARA (0.58) | RARARARBRARGNPC1RAB9A | |
| SCHEMBL8843431 | 0.79 | RARA (0.63) | RARARARBRARG | |
| SCHEMBL4757231 | 0.77 | RARA (1.00) | RARARARBRARGALDH1A1MEN1 | |
| SCHEMBL12365355 | 0.75 | RARB (0.67) | RARARARBRARG | |
| SCHEMBL12366083 | 0.75 | RARA (0.47) | RARARARBRARG | |
| SCHEMBL8028151 | 0.74 | RARB (0.62) | RARARARBRARG | |
| SCHEMBL8842937 | 0.74 | RARA (0.64) | RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618839-A | Retinoid-like compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-04-08 | — | — | US | disclosed |