Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885306 | 0.82 | MTNR1A (0.67) | MTNR1AMAPTNQO2MTNR1B | |
| SCHEMBL8885141 | 0.82 | MTNR1A (0.66) | MTNR1ANQO2MTNR1B | |
| SCHEMBL8885059 | 0.81 | MTNR1A (0.62) | MTNR1AMAPTNQO2MTNR1B | |
| SCHEMBL8885168 | 0.80 | PSMB5 (0.53) | MTNR1A | |
| SCHEMBL10222548 | 0.79 | TP53 (0.59) | TP53MTNR1AMAPTSMN1; SMN2THRB | |
| SCHEMBL7752915 | 0.78 | MTNR1A (0.83) | TP53MTNR1ANQO2MTNR1B | |
| SCHEMBL8883881 | 0.75 | MTNR1A (0.69) | MTNR1ANQO2MTNR1B | |
| SCHEMBL8884345 | 0.74 | HTR1D (0.56) | MTNR1AMAPTNQO2MTNR1B | |
| SCHEMBL8884003 | 0.74 | MTNR1A (0.56) | TP53MTNR1ASMN1; SMN2MTNR1B | |
| SCHEMBL8867452 | 0.72 | MTNR1A (0.66) | TP53MTNR1AMAPTSMN1; SMN2NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612368-A | SKIN DISORDERS, MELATONINERGIC SYSTEMS, ANTIARRHYTHMIA AGENTS OR ANTIISCHEMIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-03-18 | — | — | US | disclosed |