Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.66 |
| ▸ | NQO2 | P16083 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885306 | 0.88 | MTNR1A (0.67) | MTNR1AMTNR1BNQO2LMNATSHR | |
| SCHEMBL8884128 | 0.87 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2LMNATSHR | |
| SCHEMBL8884133 | 0.86 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2LMNATSHR | |
| SCHEMBL8885059 | 0.85 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2LMNATSHR | |
| SCHEMBL8882998 | 0.84 | MTNR1A (0.69) | MTNR1AMTNR1BNQO2LMNATSHR | |
| SCHEMBL8884731 | 0.82 | MTNR1A (0.55) | MTNR1AMTNR1BNQO2LMNATSHR | |
| SCHEMBL8884201 | 0.82 | TP53 (0.54) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL4153178 | 0.80 | MTNR1A (0.66) | MTNR1AMTNR1BNQO2LMNATSHR | |
| SCHEMBL8885168 | 0.80 | PSMB5 (0.53) | MTNR1A | |
| SCHEMBL7018941 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612368-A | SKIN DISORDERS, MELATONINERGIC SYSTEMS, ANTIARRHYTHMIA AGENTS OR ANTIISCHEMIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-03-18 | — | — | US | disclosed |