Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.42 |
| ▸ | PDE1A | P54750 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824433 | 0.91 | KDM4E (0.58) | KDM4EMAPTSLC10A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8884141 | 0.90 | MAPT (0.60) | KDM4EMAPTSLC10A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8883747 | 0.89 | SLC10A2 (0.45) | KDM4EMAPTSLC10A2ALDH1A1GAA | |
| SCHEMBL8132011 | 0.88 | MAPT (0.60) | KDM4EMAPTSLC10A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9044254 | 0.87 | KDM4E (0.54) | KDM4EMAPTSLC10A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8137949 | 0.87 | KDM4E (0.54) | KDM4EMAPTSLC10A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8883731 | 0.87 | MAPT (0.59) | KDM4EMAPTSLC10A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8121588 | 0.85 | SLC10A2 (0.53) | KDM4EMAPTSLC10A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7820569 | 0.85 | KDM4E (0.52) | KDM4EMAPTSLC10A2ALDH1A1SMN1; SMN2 | |
| Diethylamine SCHEMBL8883749 | 0.84 | GAA (0.52) | KDM4EMAPTSLC10A2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650410-A | ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-22 | — | — | US | disclosed |