Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883852 | 0.88 | MTNR1A (0.51) | MTNR1AALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL8883727 | 0.84 | MTNR1A (0.51) | MTNR1AALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL8883735 | 0.82 | MTNR1A (0.51) | MTNR1AMEN1KMT2AF2TACR1 | |
| SCHEMBL8644133 | 0.82 | MTNR1A (0.68) | MTNR1ASIRT5MEN1KMT2AATM | |
| SCHEMBL8883973 | 0.81 | MTNR1A (0.71) | MTNR1AMTNR1B | |
| SCHEMBL8961076 | 0.77 | MTNR1A (0.57) | MTNR1AALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL8882879 | 0.77 | MTNR1A (0.46) | MTNR1AALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8883983 | 0.71 | MTNR1A (0.52) | MTNR1AMEN1KMT2AATM | |
| SCHEMBL6077255 | 0.71 | MTNR1A (0.74) | MTNR1AMEN1KMT2AMTNR1B | |
| SCHEMBL8887333 | 0.70 | MTNR1A (0.70) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612368-A | SKIN DISORDERS, MELATONINERGIC SYSTEMS, ANTIARRHYTHMIA AGENTS OR ANTIISCHEMIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-03-18 | — | — | US | disclosed |