Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641021 | 0.85 | ALDH1A1 (0.61) | MTNR1AMEN1KMT2AATMPARP10 | |
| SCHEMBL6077255 | 0.85 | MTNR1A (0.74) | MTNR1AMEN1KMT2A | |
| SCHEMBL8884729 | 0.82 | MTNR1A (0.52) | MTNR1AMEN1KMT2AATMPARP10 | |
| SCHEMBL8883881 | 0.82 | MTNR1A (0.69) | MTNR1AMEN1KMT2A | |
| SCHEMBL8620465 | 0.82 | MTNR1A (1.00) | MTNR1A | |
| SCHEMBL9395412 | 0.81 | NQO2 (0.51) | MTNR1AMEN1KMT2AATMPARP10 | |
| SCHEMBL8883727 | 0.81 | MTNR1A (0.51) | MTNR1AMEN1KMT2AATMPARP10 | |
| SCHEMBL8886877 | 0.80 | MTNR1A (0.77) | MTNR1A | |
| SCHEMBL8883983 | 0.79 | MTNR1A (0.52) | MTNR1AMEN1KMT2AATM | |
| SCHEMBL8883232 | 0.79 | EPHX1 (0.52) | MTNR1AMEN1KMT2AATMPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709371-B1 | O-arylmethyl N-(thio)acyl hydroxylamines as ligands for the melatonine receptors, their processes of preparation and the pharmaceutical compositions containing them | ADIR (FR) | 1998-05-06 | — | — | EP | disclosed |
| US-5612368-A | SKIN DISORDERS, MELATONINERGIC SYSTEMS, ANTIARRHYTHMIA AGENTS OR ANTIISCHEMIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-03-18 | — | — | US | disclosed |
| EP-0709371-A1 | O-arylmethyl N-(thio)acyl hydroxylamines as ligands for the melatonine receptors, their processes of preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |