SCHEMBL8885012

SCHEMBL8885012

CC1=CC(=O)N(CCCCCCCN2C(=O)C=C(C)C2=O)C1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 5/20 0.48
FAAH O00519 3/20 0.48
ALDH1A1 P00352 2/20 0.48
LMNA P02545 2/20 0.48
HTT P42858 2/20 0.48
RECQL P46063 2/20 0.48
RAB9A P51151 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
HSP90AA1 P07900 1/20 0.48
TLR9 Q9NR96 1/20 0.48
TP53 P04637 1/20 0.48
MAPT P10636 1/20 0.48
PKM P14618 1/20 0.48
HPGD P15428 1/20 0.48
XBP1 P17861 1/20 0.48
MAPK1 P28482 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
GPR35 Q9HC97 1/20 0.48
GPR55 Q9Y2T6 1/20 0.48
PTGS1 P23219 7/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8886884 1.00 MGLL (0.48) MGLLFAAHALDH1A1LMNAHTT
SCHEMBL8886103 1.00 MGLL (0.48) MGLLFAAHALDH1A1LMNAHTT
SCHEMBL907802 1.00 MGLL (0.48) MGLLFAAHALDH1A1LMNAHTT
SCHEMBL8442748 1.00 MGLL (0.48) MGLLFAAHALDH1A1LMNAHTT
SCHEMBL8443620 1.00 MGLL (0.48) MGLLFAAHALDH1A1LMNAHTT
SCHEMBL8443081 1.00 MGLL (0.48) MGLLFAAHALDH1A1LMNAHTT
SCHEMBL8887050 1.00 MGLL (0.48) MGLLFAAHALDH1A1LMNAHTT
SCHEMBL8883684 0.98 MGLL (0.46) MGLLFAAHALDH1A1LMNAHTT
SCHEMBL8885500 0.93 MGLL (0.41) MGLLFAAHALDH1A1LMNAHTT
SCHEMBL18999087 0.92 MGLL (0.58) MGLLFAAHALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5610240-A CITRACONIC IMIDES AKZO NOBEL NV (NL) 1997-03-11 US disclosed
EP-0555288-B1 ANTI-REVERSION COAGENTS FOR RUBBER VULCANIZATION AKZO NOBEL NV (NL) 1996-06-19 EP disclosed
US-5426155-A Adjuvants which prevent loss of crosslinking in vulcanized rubbers AKZO NOBEL N.V. (NL) 1995-06-20 US disclosed