Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.60 |
| ▸ | AHCY | P23526 | 6/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.53 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877452 | 0.86 | AHCY (0.65) | PNPAHCYADORA3STING1HPRT1 | |
| SCHEMBL29325364 | 0.86 | AHCY (0.65) | PNPAHCYADORA3STING1HPRT1 | |
| SCHEMBL9078539 | 0.86 | AHCY (0.65) | PNPAHCYADORA3STING1HPRT1 | |
| SCHEMBL10767171 | 0.86 | AHCY (0.65) | PNPAHCYADORA3STING1HPRT1 | |
| SCHEMBL10767166 | 0.86 | AHCY (0.65) | PNPAHCYADORA3STING1HPRT1 | |
| SCHEMBL29323386 | 0.86 | AHCY (0.65) | PNPAHCYADORA3STING1HPRT1 | |
| SCHEMBL1713028 | 0.86 | AHCY (0.65) | PNPAHCYADORA3STING1HPRT1 | |
| SCHEMBL9367067 | 0.84 | AHCY (0.60) | PNPAHCYADORA3STING1HPRT1 | |
| SCHEMBL10516308 | 0.84 | AHCY (0.60) | PNPAHCYADORA3STING1HPRT1 | |
| SCHEMBL10516867 | 0.84 | AHCY (0.60) | PNPAHCYADORA3STING1HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631259-A | PURINE BASE DERIVATIVES FOR NUCLEOSIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-20 | — | — | US | disclosed |
| EP-0521463-A2 | Substituted cyclic cycloalkyltriols, process, intermediates for their preparation and their use as antiviral and antiparasitic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-01-07 | — | — | EP | disclosed |