Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 18/20 | 0.75 |
| ▸ | HTR1D | P28221 | 18/20 | 0.75 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8887313 | 0.99 | HTR1A (0.73) | HTR1AHTR1DADRA1DADRA1AADRA1B | |
| SCHEMBL8887169 | 0.87 | HTR1A (0.78) | HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL8864153 | 0.84 | HTR1A (0.95) | HTR1AHTR1DADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL8864158 | 0.84 | HTR1A (0.95) | HTR1AHTR1DADRA1DADRA1AADRA1B | |
| SCHEMBL8886279 | 0.82 | HTR1A (0.75) | HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL8886666 | 0.81 | HTR1A (0.74) | HTR1AHTR1D | |
| SCHEMBL8885256 | 0.81 | HTR1A (0.78) | HTR1AHTR1DADRA1DADRA1AADRA1B | |
| SCHEMBL6049991 | 0.80 | HTR1A (0.66) | HTR1AHTR1DADRA1DADRA1AADRA1B | |
| SCHEMBL6049929 | 0.80 | HTR1A (0.66) | HTR1AHTR1DADRA1DADRA1AADRA1B | |
| SCHEMBL8889257 | 0.80 | HTR1A (0.49) | HTR1AHTR1DADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691344-A | Vasoconstrictive substituted dihydropyranopyridines | JANSSEN PHARMACEUTICA, N.V. (BE) | 1997-11-25 | — | — | US | claimed |
| US-5691344-A | Vasoconstrictive substituted dihydropyranopyridines | JANSSEN PHARMACEUTICA, N.V. (BE) | 1997-11-25 | — | — | US | disclosed |