SCHEMBL888544

SCHEMBL888544

CCOC(=O)C(COC)(c1ccccc1)C(C)C

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CACNA1G O43497 4/20 0.51
PIN1 Q13526 2/20 0.48
KCNN4 O15554 1/20 0.40
MMP8 P22894 2/20 0.40
ALDH1A1 P00352 2/20 0.40
RECQL P46063 1/20 0.40
NPSR1 Q6W5P4 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
GAA P10253 1/20 0.39
POLB P06746 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888547 0.88 CACNA1G (0.48) CACNA1GPIN1MMP8ALDH1A1RECQL
SCHEMBL888286 0.86 KCNN4 (0.51) CACNA1GKCNN4ALDH1A1MEN1KMT2A
SCHEMBL11842386 0.84 CACNA1G (0.52) CACNA1GPIN1MMP8ALDH1A1RECQL
SCHEMBL818203 0.80 CYP1A2 (0.41) CACNA1GKCNN4ALDH1A1KMT2ACHRM2
SCHEMBL14874329 0.79 CACNA1G (0.48) CACNA1GPIN1ALDH1A1MEN1KMT2A
SCHEMBL888331 0.77 PIN1 (0.42) CACNA1GPIN1KCNN4MMP8ALDH1A1
SCHEMBL27739492 0.77 PIN1 (0.44) CACNA1GPIN1MMP8ALDH1A1RECQL
SCHEMBL16732173 0.76 PIN1 (0.50) CACNA1GPIN1KCNN4MMP8ALDH1A1
SCHEMBL28481278 0.76 PIN1 (0.46) PIN1KCNN4MMP8ALDH1A1RECQL
SCHEMBL28041493 0.75 CACNA1G (0.45) CACNA1GPIN1MMP8ALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed