Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885438 | 1.00 | ALDH1A1 (0.59) | ALDH1A1HTTCYP26A1HSD11B1ACHE | |
| SCHEMBL3438339 | 0.97 | ALDH1A1 (0.54) | ALDH1A1HTTCYP26A1HSD11B1ACHE | |
| SCHEMBL3438340 | 0.97 | ALDH1A1 (0.54) | ALDH1A1HTTCYP26A1HSD11B1ACHE | |
| SCHEMBL28010017 | 0.76 | IKBKB (0.60) | ALDH1A1HTTHSD11B1ACHEMAPT | |
| SCHEMBL29169553 | 0.76 | ALDH1A1 (0.63) | ALDH1A1HTTCYP26A1HSD11B1ACHE | |
| SCHEMBL1524256 | 0.76 | ALDH1A1 (0.58) | ALDH1A1HTTHSD11B1MAPTSMN1; SMN2 | |
| SCHEMBL17077393 | 0.76 | HTT (0.58) | ALDH1A1HTTHSD11B1ACHEMAPT | |
| SCHEMBL28426543 | 0.76 | IKBKB (0.60) | ALDH1A1HTTHSD11B1ACHEMAPT | |
| SCHEMBL29169562 | 0.76 | HSD11B1 (0.77) | ALDH1A1HTTCYP26A1HSD11B1MAPT | |
| SCHEMBL1524257 | 0.76 | ALDH1A1 (0.58) | ALDH1A1HTTHSD11B1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639918-A | Intermediate compounds useful in the preparation of fungicidal compositions containing (benzylidene)-azolylmethyclycloalkane | RHONE-POULENC AGROCHIMIE (FR) | 1997-06-17 | — | — | US | disclosed |
| CN-1031971-C | (Benzylidene)-azolylmethylcycloalkane and use as fungicide | RHONE POULENC AGROCHIMIE (FR) | 1996-06-12 | — | — | CN | disclosed |
| EP-0378953-B1 | Benzylidene azolyl methyl cycloalkane and its use as a fungicide | RHONE POULENC AGROCHIMIE (FR) | 1996-06-05 | — | — | EP | disclosed |
| US-5380743-A | Fungicidal compositions containing (benzylidene)-azolymethylcycloalkane | RHONE-POULENC AGROCHIMIE (FR) | 1995-01-10 | — | — | US | disclosed |
| US-5256683-A | Plant protective agent 1H-1,2,4-triazolylmethylcycloalkane or -alkene benzylidene | RHONE-POULENC AGROCHIMIE (FR) | 1993-10-26 | — | — | US | disclosed |
| CN-1044814-A | (benzylidene) azoles ylmethyl naphthenic hydrocarbon and sterilant thereof | RHONE POULENC AGROCHIMIE (FR) | 1990-08-22 | — | — | CN | disclosed |
| EP-0378953-A1 | Benzylidene azolyl methyl cycloalkane and its use as a fungicide | RHONE-POULENC AGROCHIMIE (FR) | 1990-07-25 | — | — | EP | disclosed |