Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170835 | 0.83 | GDA (0.35) | GDAXDHACHE | |
| SCHEMBL10766157 | 0.61 | PNP (0.38) | — | |
| SCHEMBL142922 | 0.61 | QTRT1 (0.42) | XDH | |
| SCHEMBL14793670 | 0.61 | DPYD (0.31) | GDA | |
| SCHEMBL14793521 | 0.61 | TYMP (0.35) | GDA | |
| SCHEMBL13702507 | 0.60 | ALDH1A1 (0.36) | GDAXDHACHE | |
| SCHEMBL9008314 | 0.58 | GDA (0.71) | GDAACHE | |
| SCHEMBL11100644 | 0.57 | — | — | |
| SCHEMBL3718306 | 0.57 | TYMP (0.31) | — | |
| SCHEMBL1919722 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814407-B2 | Multiple coupling and oxidation method | ROCHE INNOVATION CENTER COPENHAGEN A/S (CH) | 2023-11-14 | — | — | US | claimed |
| US-11142545-B2 | Synthesis of thiolated oligonucleotides without a capping step | BIOGEN MA INC. (US) | 2021-10-12 | — | — | US | claimed |
| US-10947262-B2 | Hydrophobic interaction chromatography for purification of oligonucleotides | BIOGEN MA INC. (US) | 2021-03-16 | — | — | US | claimed |
| US-10669301-B2 | Phosphoramidite building blocks for sugar-conjugated oligonucleotides | AM CHEMICALS LLC (US) | 2020-06-02 | — | — | US | claimed |
| US-20180369268-A1 | METHODS FOR IDENTIFYING INHIBITORS OF \"STIMULATOR OF INTERFERON GENE\"- DEPENDENT INTERFERON PRODUCTION | Aduro Biotech, Inc. (US) | 2018-12-27 | — | — | US | claimed |
| US-20180362572-A1 | PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES | AM CHEMICALS LLC (US) | 2018-12-20 | — | — | US | claimed |
| US-10087208-B2 | Phosphoramidite building blocks for sugar-conjugated oligonucleotides | AM CHEMICALS LLC (US) | 2018-10-02 | — | — | US | claimed |
| WO-2017106740-A1 | METHODS FOR IDENTIFYING INHIBITORS OF \"STIMULATOR OF INTERFERON GENE\"-DEPENDENT INTERFERON PRODUCTION | Aduro Biotech, Inc. (US) | 2017-06-22 | — | — | WO | claimed |
| US-9303056-B2 | Monomer for synthesis of RNA, method for producing same, and method for producing RNA | KOCHI UNIVERSITY (JP) | 2016-04-05 | — | — | US | claimed |
| WO-2009120358-A1 | OLIGOMER-NITROGENOUS BASE CONJUGATES | NEKTAR THERAPEUTICS (US) | 2009-10-01 | — | — | WO | claimed |
| EP-0454427-A1 | Antiretroviral bases | Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic (CZ) | 1991-10-30 | — | — | EP | claimed |
| US-5015739-A | Processes for preparation of cyclopentyl purine derivatives | SCHERING CORPORATION (US) | 1991-05-14 | — | — | US | claimed |
| US-4999428-A | Process for preparing cyclopentyl purine derivatives | SCHERING CORPORATION (US) | 1991-03-12 | — | — | US | claimed |
| EP-0412995-A1 | CYCLOPENTYL PURINE DERIVATIVES, INTERMEDIATES AND PROCESSES FOR PREPARATION | SCHERING CORPORATION (US) | 1991-02-20 | — | — | EP | claimed |
| EP-0253412-B1 | N-PHOSPHONYLMETHOXYALKYL DERIVATIVES OF PYRIMIDINE AND PURINE BASES, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREFROM WITH ANTIVIRAL ACTIVITY | Ceskoslovenska akademie ved (CS) | 1990-10-31 | — | — | EP | claimed |
| WO-1989010367-A1 | CYCLOPENTYL PURINE DERIVATIVES, INTERMEDIATES AND PROCESSES FOR PREPARATION | SCHERING CORPORATION (US) | 1989-11-02 | — | — | WO | claimed |
| EP-0338842-A1 | Cyclopentyl purine derivatives, intermediates and processes for preparation | SCHERING CORPORATION (US) | 1989-10-25 | — | — | EP | claimed |
| EP-0278501-A2 | Nucleotide analogs, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-08-17 | — | — | EP | claimed |
| EP-0253412-A2 | N-Phosphonylmethoxyalkyl derivatives of pyrimidine and purine bases, methods for their preparation and pharmaceutical compositions therefrom with antiviral activity | Ceskoslovenska akademie ved (CS) | 1988-01-20 | — | — | EP | claimed |
| EP-0236935-A2 | Carboxylic purine nucleosides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-16 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10669301-B2 | Phosphoramidite building blocks for sugar-conjugated oligonucleotides | DERA, FBP1, PNKP | GDA 402/4885XDH 2594/4885ACHE 3886/4885 |
| US-20180362572-A1 | PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES | DERA, TYMP, PAICS | GDA 488/4885XDH 2883/4885ACHE 3466/4885 |
| US-10087208-B2 | Phosphoramidite building blocks for sugar-conjugated oligonucleotides | DERA, TYMP, PAICS | GDA 488/4885XDH 2883/4885ACHE 3466/4885 |
| US-11814407-B2 | Multiple coupling and oxidation method | RNGTT, PCNA, TYMP | GDA 1091/4885XDH 1231/4885ACHE 2894/4885 |
| US-20180369268-A1 | METHODS FOR IDENTIFYING INHIBITORS OF \"STIMULATOR OF INTERFERON GENE\"- DEPENDENT INTERFERON PRODUCTION | STING1, CGAS, IRF3 | GDA 83/4885XDH 321/4885ACHE 4449/4885 |
| US-10947262-B2 | Hydrophobic interaction chromatography for purification of oligonucleotides | IPO5, IPO4, PHAX | GDA 1745/4885XDH 4434/4885ACHE 4120/4885 |
| US-11142545-B2 | Synthesis of thiolated oligonucleotides without a capping step | RNGTT, NSUN3, NSUN2 | GDA 1581/4885XDH 3059/4885ACHE 2033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.