Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885687 | 1.00 | CAPN1 (0.42) | CAPN1TAS1R3TAS1R1MAPTTHRB | |
| SCHEMBL7434947 | 0.91 | TAS1R3 (0.50) | TAS1R3TAS1R1THRBCTSKLMNA | |
| SCHEMBL7312803 | 0.89 | CAPN1 (0.53) | CAPN1TAS1R3TAS1R1MAPTTHRB | |
| SCHEMBL7312816 | 0.89 | CAPN1 (0.53) | CAPN1TAS1R3TAS1R1MAPTTHRB | |
| SCHEMBL7433580 | 0.85 | MMP3 (0.36) | MAPTPOLBPTGS2CTSBMMP3 | |
| SCHEMBL7433589 | 0.85 | MMP3 (0.36) | MAPTPOLBPTGS2CTSBMMP3 | |
| SCHEMBL7303780 | 0.84 | POLB (0.48) | MAPTPOLBCTSKCTSBCTSS | |
| SCHEMBL7303804 | 0.84 | POLB (0.48) | MAPTPOLBCTSKCTSBCTSS | |
| SCHEMBL7312904 | 0.82 | POLB (0.46) | POLBCTSKCTSBCTSSMMP3 | |
| SCHEMBL7312916 | 0.82 | POLB (0.46) | POLBCTSKCTSBCTSSMMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |