Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398807 | 0.92 | CA12 (0.45) | CA12CA9CA1CA2MEN1 | |
| SCHEMBL88858 | 0.92 | CA12 (0.45) | CA12CA9CA1CA2MEN1 | |
| Hydrochloric Acid SCHEMBL9756819 | 0.90 | CA12 (0.44) | CA12CA9CA1CA2MEN1 | |
| SCHEMBL28201382 | 0.90 | CA12 (0.44) | CA12CA9CA1CA2MEN1 | |
| Acetic Acid SCHEMBL6200962 | 0.85 | CA12 (0.38) | CA12CA9CA1CA2MEN1 | |
| Oxazole SCHEMBL4863479 | 0.74 | CA12 (0.33) | CA12CA9CA1CA2 | |
| Hydrochlorthiazide SCHEMBL6036314 | 0.74 | CA12 (0.33) | CA12CA9CA1CA2 | |
| SCHEMBL29429784 | 0.73 | CA12 (0.42) | CA12CA9CA1CA2GPR3 | |
| SCHEMBL11256812 | 0.71 | CA12 (0.35) | CA12CA9CA1CA2MEN1 | |
| SCHEMBL5613160 | 0.68 | CA12 (0.40) | CA12CA9CA1CA2GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003074-A | N-fluorinated sulfonamides | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |