Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88858 | 0.81 | CA12 (0.45) | CA12CA1CA2CA9 | |
| SCHEMBL29398807 | 0.81 | CA12 (0.45) | CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL9756819 | 0.79 | CA12 (0.44) | CA12CA1CA2CA9 | |
| SCHEMBL28201382 | 0.79 | CA12 (0.44) | CA12CA1CA2CA9 | |
| Isobutane SCHEMBL9756824 | 0.74 | CA12 (0.40) | CA12CA1CA2CA9 | |
| Hydrochlorthiazide SCHEMBL6036314 | 0.72 | CA12 (0.33) | CA12CA1CA2CA9 | |
| Acetic Acid SCHEMBL6200962 | 0.71 | CA12 (0.38) | CA12CA1CA2CA9 | |
| SCHEMBL29429784 | 0.68 | CA12 (0.42) | CA12CA1CA2CA9 | |
| Triphenylene SCHEMBL21381928 | 0.67 | LMNA (0.32) | — | |
| Naphthalene SCHEMBL303948 | 0.67 | CYP2A6 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7453000-B2 | Substituted oxazolobenzoisothiazole dioxide derivatives method for production and use thereof | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-11-18 | — | — | US | disclosed |
| US-20070149511-A1 | SUBSTITUTED OXAZOLOBENZOISOTHIAZOLE DIOXIDE DERIVATIVES METHOD FOR PRODUCTION AND USE THEREOF | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149511-A1 | SUBSTITUTED OXAZOLOBENZOISOTHIAZOLE DIOXIDE DERIVATIVES METHOD FOR PRODUCTION AND USE THEREOF | SLC5A2, SLC5A1, NOX4 | CA12 451/4885CA1 971/4885CA2 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.