Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884451 | 0.86 | HSD17B10 (0.46) | HSD17B10MAPTESR2MAOBALDH1A1 | |
| SCHEMBL16997512 | 0.72 | PDE3B (0.45) | HSD17B10MAPTMAOBALDH1A1KDM4E | |
| SCHEMBL891520 | 0.71 | MAOB (0.53) | HSD17B10MAPTESR2MAOBALDH1A1 | |
| SCHEMBL14923238 | 0.70 | MAOB (0.53) | HSD17B10MAPTESR2MAOBALDH1A1 | |
| SCHEMBL8886041 | 0.70 | ATM (0.50) | HSD17B10MAPTESR2MAOBALDH1A1 | |
| SCHEMBL8883187 | 0.69 | OPRM1 (0.54) | HSD17B10MAPTESR2ALDH1A1 | |
| SCHEMBL14906619 | 0.68 | HSD17B10 (0.46) | HSD17B10MAPTESR2MAOBALDH1A1 | |
| SCHEMBL8882891 | 0.68 | OPRM1 (0.53) | HSD17B10MAPTESR2ALDH1A1KDM4E | |
| SCHEMBL8885794 | 0.68 | KDM4E (0.49) | HSD17B10MAPTESR2MAOBALDH1A1 | |
| SCHEMBL8885548 | 0.68 | OPRM1 (0.53) | HSD17B10MAPTESR2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661169-A | HAVE AFFINITY FOR VASOPRESSIN AND/OR OXYTOCIN RECEPTORS | SANOFI (FR) | 1997-08-26 | — | — | US | disclosed |
| US-5585394-A | INHIBITOR, ANTAGONIST OF VASOPRESSIN OR OXYTOCIN | SANOFI (FR) | 1996-12-17 | — | — | US | disclosed |
| EP-0694536-A1 | 1-Benzyl-1,3-dihydro-2H-benzimidazol-2-one derivatives, their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1996-01-31 | — | — | EP | disclosed |
| EP-0636614-A1 | Derivatives of 1-benzenesulfonyl-1,3-dihydro-2H-benzimidazol-2-one, their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1995-02-01 | — | — | EP | disclosed |