Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884111 | 0.99 | TBXAS1 (0.83) | TBXAS1TBXA2R | |
| SCHEMBL8882539 | 0.96 | TBXAS1 (0.83) | TBXAS1TBXA2R | |
| SCHEMBL8882712 | 0.90 | TBXAS1 (0.83) | TBXAS1TBXA2R | |
| SCHEMBL8884653 | 0.90 | TBXAS1 (0.83) | TBXAS1TBXA2R | |
| SCHEMBL8883679 | 0.90 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL8882148 | 0.87 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL8883931 | 0.83 | TBXAS1 (0.63) | TBXAS1TBXA2R | |
| SCHEMBL9734305 | 0.82 | TBXAS1 (0.84) | TBXAS1 | |
| SCHEMBL8882120 | 0.79 | TBXAS1 (0.65) | TBXAS1TBXA2R | |
| SCHEMBL8884708 | 0.79 | TBXAS1 (0.67) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681961-A | TREATMENT AND/OR PREVENTION OF THROMBOEMBOLIC DISORDERS, ARTERIOSCLEROSIS, METASTASIS. ISCHEMIA, ASTHMA, ALLERGIES | DR. KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |
| EP-0397044-B1 | Arylsulfonamides, medicines containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1995-12-27 | — | — | EP | disclosed |
| US-5426119-A | Thromboxane antagonists | DR. KARL THOMAE GMBH (DE) | 1995-06-20 | — | — | US | disclosed |
| US-5294626-A | Thromboxane synthesis inhibitors and anticoagulants | DR. KARL THOMAS GMBH (DE) | 1994-03-15 | — | — | US | disclosed |