Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29020440 | 0.83 | TSHR (0.50) | TSHRALDH1A1THRB | |
| SCHEMBL25774904 | 0.77 | TSHR (0.61) | TSHRALDH1A1THRB | |
| SCHEMBL27398964 | 0.77 | TSHR (0.61) | TSHRALDH1A1THRB | |
| SCHEMBL150581 | 0.77 | TSHR (0.61) | TSHRALDH1A1THRB | |
| SCHEMBL3098779 | 0.77 | TSHR (0.44) | TSHRALDH1A1THRB | |
| SCHEMBL23493794 | 0.76 | TSHR (0.64) | TSHRALDH1A1THRB | |
| SCHEMBL5345238 | 0.76 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL4399857 | 0.76 | TSHR (0.64) | TSHRALDH1A1THRB | |
| SCHEMBL12657026 | 0.76 | TSHR (0.59) | TSHRALDH1A1THRB | |
| SCHEMBL8605073 | 0.75 | TSHR (0.53) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679418-A | A POLYURETHANE BLENDS COMPRISING FIRST POLYURETHANE DIOL FROM A TERTIARY AMINO GROUP, A POLYMERIC DIOL OF POLYESTERS, POLYCARBONATES, POLYLACTONES OR POLYETHERS, THE SECOND POLYURETHANE HAVING DIMETHYLSILOXANE GROUP; DURABILITY | KURARAY CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |