Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569467 | 0.82 | TSHR (0.51) | TSHRALDH1A1KDM4EELANEGPR174 | |
| SCHEMBL3683113 | 0.79 | TSHR (0.44) | TSHRALDH1A1KDM4EELANEGPR174 | |
| SCHEMBL8886282 | 0.76 | TSHR (0.53) | TSHRALDH1A1 | |
| SCHEMBL11465517 | 0.73 | TSHR (0.47) | TSHRALDH1A1KDM4EADRB2ADRB1 | |
| SCHEMBL16595000 | 0.73 | TDP1 (0.41) | TSHRALDH1A1KDM4EELANETDP1 | |
| SCHEMBL29020440 | 0.73 | TSHR (0.50) | TSHRALDH1A1 | |
| SCHEMBL2574848 | 0.72 | ALDH1A1 (0.41) | TSHRALDH1A1KDM4EELANEGPR174 | |
| SCHEMBL3180135 | 0.72 | TSHR (0.53) | TSHRALDH1A1ELANETDP1POLB | |
| SCHEMBL13872067 | 0.72 | LMNA (0.52) | TSHRALDH1A1GPR174TDP1HPGD | |
| SCHEMBL23115524 | 0.71 | TSHR (0.49) | TSHRALDH1A1GPR174TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007083154-A1 | AMPHIPATHIC POLYMER CONJUGATES FOR SOLUBILISATION OF HYDROPHOBIC PROTEINS | BABRAHAM BIOSCIENCE TECHNOLOGIES LIMITED (GB) | 2007-07-26 | — | — | WO | disclosed |