SCHEMBL8886404

SCHEMBL8886404

CCCCCC(CCS)CCCCC

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
OPRM1 P35372 1/20 0.42
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
DNM1 Q05193 5/20 0.38
TSHR P16473 2/20 0.37
CYP3A4 P08684 1/20 0.37
THRB P10828 1/20 0.37
FDPS P14324 3/20 0.36
GPR84 Q9NQS5 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11078123 0.97 LMNA (0.54) LMNAOPRM1ALDH1A1DNM1TSHR
SCHEMBL7754804 0.97 LMNA (0.48) LMNAOPRM1ALDH1A1TDP1DNM1
SCHEMBL23327936 0.97 LMNA (0.54) LMNAOPRM1ALDH1A1DNM1TSHR
SCHEMBL28990462 0.97 LMNA (0.54) LMNAOPRM1ALDH1A1DNM1TSHR
SCHEMBL28990460 0.97 LMNA (0.54) LMNAOPRM1ALDH1A1DNM1TSHR
SCHEMBL4610132 0.95 LMNA (0.46) LMNAOPRM1ALDH1A1TDP1DNM1
SCHEMBL4609781 0.93 LMNA (0.50) LMNAOPRM1DNM1TSHRTHRB
SCHEMBL12226204 0.93 LMNA (0.50) LMNAOPRM1DNM1TSHRTHRB
SCHEMBL11651348 0.93 LMNA (0.50) LMNAOPRM1ALDH1A1DNM1TSHR
SCHEMBL11649242 0.93 LMNA (0.50) LMNAOPRM1ALDH1A1DNM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105985774-B The application of nanocrystalline-ligand complex, preparation method, printing material and printing material 纳晶科技股份有限公司 2019-05-28 CN claimed
CN-105985774-B The application of nanocrystalline-ligand complex, preparation method, printing material and printing material 纳晶科技股份有限公司 2019-05-28 CN disclosed
US-5650430-A Radicicol derivatives, their preparation and their anti-tumor activity SANKYO COMPANY, LIMITED (JP) 1997-07-22 US disclosed
US-5597846-A ESTERS OF RADICICOL SANKYO COMPANY, LIMITED (JP) 1997-01-28 US disclosed
WO-1991018905-A1 RADICICOL DERIVATIVES, THEIR PREPARATION AND THEIR ANTI-TUMOR ACTIVITY SANKYO COMPANY LIMITED (JP) 1991-12-12 WO disclosed
EP-0460950-A1 Radicicol derivatives, their preparation and their anti-tumour activity Sankyo Company Limited (JP) 1991-12-11 EP disclosed