SCHEMBL4610132

SCHEMBL4610132

CCCCCC(CCC)CCS

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
OPRM1 P35372 1/20 0.39
ALDH1A1 P00352 3/20 0.36
TDP1 Q9NUW8 1/20 0.36
DNM1 Q05193 2/20 0.35
TSHR P16473 2/20 0.34
CYP3A4 P08684 1/20 0.34
FDPS P14324 4/20 0.33
THRB P10828 1/20 0.33
GPR84 Q9NQS5 2/20 0.32
SPHK1 Q9NYA1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12226204 0.98 LMNA (0.50) LMNAOPRM1DNM1TSHRFDPS
SCHEMBL4609781 0.98 LMNA (0.50) LMNAOPRM1DNM1TSHRFDPS
SCHEMBL8886404 0.95 LMNA (0.50) LMNAOPRM1ALDH1A1TDP1DNM1
SCHEMBL23327936 0.92 LMNA (0.54) LMNAOPRM1ALDH1A1DNM1TSHR
SCHEMBL11078123 0.92 LMNA (0.54) LMNAOPRM1ALDH1A1DNM1TSHR
SCHEMBL18256102 0.92 ALDH1A1 (0.42) LMNAALDH1A1TDP1DNM1TSHR
SCHEMBL28990460 0.92 LMNA (0.54) LMNAOPRM1ALDH1A1DNM1TSHR
SCHEMBL28990462 0.92 LMNA (0.54) LMNAOPRM1ALDH1A1DNM1TSHR
SCHEMBL7754804 0.92 LMNA (0.48) LMNAOPRM1ALDH1A1TDP1DNM1
SCHEMBL11651348 0.88 LMNA (0.50) LMNAOPRM1ALDH1A1DNM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105985774-B The application of nanocrystalline-ligand complex, preparation method, printing material and printing material 纳晶科技股份有限公司 2019-05-28 CN claimed
CN-105985774-A Nanocrystalline-ligand compound, preparation method of nanocrystalline-ligand compound, printing material and use of printing material 纳晶科技股份有限公司 2016-10-05 CN claimed
CN-105985774-B The application of nanocrystalline-ligand complex, preparation method, printing material and printing material 纳晶科技股份有限公司 2019-05-28 CN disclosed
CN-105985774-A Nanocrystalline-ligand compound, preparation method of nanocrystalline-ligand compound, printing material and use of printing material 纳晶科技股份有限公司 2016-10-05 CN disclosed
US-8288155-B2 Biomolecular attachment sites on microelectronic arrays and methods thereof GAMIDA FOR LIFE B.V. (NL) 2012-10-16 US disclosed
US-20090069198-A1 Biomolecular Attachment Sites on Microelectronic Arrays and Methods Thereof ADOR DIAGNOSTICS S.R.L. (IT) 2009-03-12 US disclosed
EP-1976505-A1 COMBRETASTATIN DERIVATIVES AND RELATED THERAPEUTIC METHODS Abraxis BioScience, Inc. (US) 2008-10-08 EP disclosed
WO-2007059118-A1 COMBRETASTATIN DERIVATIVES AND RELATED THERAPEUTIC METHODS ABRAXIS BIOSCIENCE, INC. (US) 2007-05-24 WO disclosed
US-5650430-A Radicicol derivatives, their preparation and their anti-tumor activity SANKYO COMPANY, LIMITED (JP) 1997-07-22 US disclosed
US-5597846-A ESTERS OF RADICICOL SANKYO COMPANY, LIMITED (JP) 1997-01-28 US disclosed
WO-1991018905-A1 RADICICOL DERIVATIVES, THEIR PREPARATION AND THEIR ANTI-TUMOR ACTIVITY SANKYO COMPANY LIMITED (JP) 1991-12-12 WO disclosed
EP-0460950-A1 Radicicol derivatives, their preparation and their anti-tumour activity Sankyo Company Limited (JP) 1991-12-11 EP disclosed