Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883891 | 0.91 | MAPT (0.46) | GAAPOLBKDM4ESLC10A2MAPT | |
| SCHEMBL8882481 | 0.91 | SLC10A2 (0.44) | GAAPOLBKDM4ESLC10A2MAPT | |
| SCHEMBL8137960 | 0.91 | SLC10A2 (0.54) | GAAPOLBKDM4ESLC10A2MAPT | |
| SCHEMBL8883747 | 0.88 | SLC10A2 (0.45) | GAAPOLBKDM4ESLC10A2MAPT | |
| SCHEMBL8132011 | 0.87 | MAPT (0.60) | GAAPOLBKDM4ESLC10A2MAPT | |
| SCHEMBL8139078 | 0.86 | SLC10A2 (0.51) | GAAPOLBKDM4ESLC10A2MAPT | |
| SCHEMBL7820772 | 0.85 | GAA (0.50) | GAAPOLBKDM4ESLC10A2MAPT | |
| Hydrochloric Acid SCHEMBL8124959 | 0.85 | SLC10A2 (0.50) | GAAKDM4ESLC10A2MAPTALDH1A1 | |
| SCHEMBL7823994 | 0.82 | GAA (0.47) | GAAPOLBKDM4ESLC10A2MAPT | |
| SCHEMBL8886772 | 0.82 | SLC10A2 (0.56) | GAAKDM4ESLC10A2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650410-A | ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0749426-A1 | QUINOLINE OR QUINAZOLINE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS, IN PARTICULAR FOR TREATING ARTHRITIS | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995024394-A1 | QUINOLINE OR QUINAZOLINE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS, IN PARTICULAR FOR TREATING ARTHRITIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |