Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | GLA | P06280 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143138 | 0.78 | KDM4E (0.57) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL4343748 | 0.78 | ALDH1A1 (0.73) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL2748825 | 0.78 | ALDH1A1 (0.73) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL7218005 | 0.78 | KDM4E (0.60) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL8242765 | 0.76 | ALDH1A1 (0.57) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL24853492 | 0.75 | ALDH1A1 (0.56) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL30173777 | 0.71 | KDM4E (1.00) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL1101766 | 0.71 | KDM4E (1.00) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL8143031 | 0.71 | KDM4E (0.58) | KDM4EALDH1A1MAPTGLAHPGD | |
| SCHEMBL8128525 | 0.71 | KDM4E (0.58) | KDM4EALDH1A1MAPTGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597823-A | TREATING BENIGN PROSTATIC HYPERPLASIA | ABBOTT LABORATORIES (US) | 1997-01-28 | — | — | US | disclosed |