Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887766 | 0.85 | IDO1 (0.32) | — | |
| SCHEMBL8890048 | 0.83 | MAPT (0.35) | ALDH1A1CYP3A4MAPTCETP | |
| SCHEMBL8891507 | 0.80 | CDC25B (0.37) | ALDH1A1MAPTCETP | |
| SCHEMBL8889029 | 0.75 | CETP (0.33) | CETP | |
| SCHEMBL3598687 | 0.74 | FFAR4 (0.40) | ALDH1A1MAPT | |
| SCHEMBL5723233 | 0.70 | PDE4A (0.43) | ALDH1A1MAPTCETP | |
| SCHEMBL8888634 | 0.68 | MAPT (0.34) | MAPT | |
| SCHEMBL8889142 | 0.67 | CA12 (0.36) | ALDH1A1MAPT | |
| SCHEMBL6607683 | 0.65 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL5722906 | 0.64 | FFAR4 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656659-A | SUBSTITUTED DIHYDROBENZOFURAN COMPOUNDS | T CELL SCIENCES, INC. (US) | 1997-08-12 | — | — | US | disclosed |
| US-5401767-A | Compounds which inhibit complement and/or suppress immune activity | T CELL SCIENCES, INC. (US) | 1995-03-28 | — | — | US | disclosed |
| US-5366986-A | SPIROBENZOFURAN-2(3H)-CYCLOALKANE COMPOUNDS | T CELL SCIENCES, INC. (US) | 1994-11-22 | — | — | US | disclosed |
| US-5173499-A | 4-Methoxyspiro(benzofuran-2,1'-cyclohexane)-7-N-methyl-carboxamides and derivatives; autoimmune diseases; antiischemic agents; respiratory system disorders | T CELL SCIENCES, INC. (US) | 1992-12-22 | — | — | US | disclosed |