Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA7 | P43166 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | GRK6 | P43250 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891507 | 0.88 | CDC25B (0.37) | CNR2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL8888634 | 0.86 | MAPT (0.34) | MAPT | |
| SCHEMBL8888254 | 0.79 | CA12 (0.34) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8887766 | 0.79 | IDO1 (0.32) | — | |
| SCHEMBL8890048 | 0.75 | MAPT (0.35) | MAPTALDH1A1KDM4ETDP1RAB9A | |
| SCHEMBL9319161 | 0.68 | MTNR1A (0.35) | MAPTKDM4E | |
| SCHEMBL8890725 | 0.68 | MTNR1A (0.35) | MAPTKDM4E | |
| SCHEMBL8887291 | 0.67 | ALDH1A1 (0.32) | MAPTALDH1A1 | |
| SCHEMBL17874455 | 0.64 | CA12 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14290549 | 0.64 | CA12 (0.53) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656659-A | SUBSTITUTED DIHYDROBENZOFURAN COMPOUNDS | T CELL SCIENCES, INC. (US) | 1997-08-12 | — | — | US | disclosed |
| US-5401767-A | Compounds which inhibit complement and/or suppress immune activity | T CELL SCIENCES, INC. (US) | 1995-03-28 | — | — | US | disclosed |
| US-5366986-A | SPIROBENZOFURAN-2(3H)-CYCLOALKANE COMPOUNDS | T CELL SCIENCES, INC. (US) | 1994-11-22 | — | — | US | disclosed |
| US-5173499-A | 4-Methoxyspiro(benzofuran-2,1'-cyclohexane)-7-N-methyl-carboxamides and derivatives; autoimmune diseases; antiischemic agents; respiratory system disorders | T CELL SCIENCES, INC. (US) | 1992-12-22 | — | — | US | disclosed |