Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 2/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602471 | 0.88 | NPC1 (0.46) | ADORA3KDRFLT1FLT4STAT3 | |
| SCHEMBL8886656 | 0.82 | ABL1 (0.45) | ADORA3KDRFLT1FLT4 | |
| SCHEMBL8886688 | 0.80 | KDR (0.45) | ADORA3KDRFLT1FLT4TRPV1 | |
| SCHEMBL8887522 | 0.79 | KDM4E (0.47) | ADORA3 | |
| SCHEMBL15598639 | 0.76 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL7746616 | 0.75 | KDR (0.65) | ADORA3KDRFLT1FLT4PTPN1 | |
| SCHEMBL7601915 | 0.74 | STAT3 (0.41) | KDRSTAT3STAT1TRPV1PTPN1 | |
| SCHEMBL7746620 | 0.74 | KDR (0.57) | ADORA3KDRFLT1FLT4TOP2A | |
| SCHEMBL8885188 | 0.70 | KMT2A (0.46) | STAT3STAT1PTPN1 | |
| SCHEMBL16482282 | 0.69 | HDAC4 (0.46) | ADORA3KDRMAPK14PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631379-A | CYCLIZATION REACTION OF PERFLUOROALKANOYLAMINO NITRILE WITH ACYL HALIDE | AMERICAN CYANAMID COMPANY (US) | 1997-05-20 | — | — | US | claimed |