Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | RXRB | P28702 | 3/20 | 0.35 |
| ▸ | RXRG | P48443 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CDH1 | P12830 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602471 | 0.86 | NPC1 (0.46) | STAT3STAT1CNR1MEN1KMT2A | |
| SCHEMBL8885188 | 0.83 | KMT2A (0.46) | STAT3STAT1PTPN1GPR35KMT2A | |
| SCHEMBL8887445 | 0.74 | ADORA3 (0.49) | STAT3STAT1PTPN1KDRTRPV1 | |
| SCHEMBL8886688 | 0.73 | KDR (0.45) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL5310221 | 0.70 | KDM4E (0.43) | STAT3STAT1MEN1KMT2AKDM4E | |
| SCHEMBL27850006 | 0.70 | KDM4E (0.38) | STAT3STAT1DHODHKDM4EHDAC4 | |
| SCHEMBL8148454 | 0.70 | RXRA (0.51) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL21339924 | 0.65 | HDAC6 (0.44) | HDAC4HDAC6 | |
| SCHEMBL21332119 | 0.65 | DHODH (0.46) | DHODHKDM4EHDAC4HDAC6KDR | |
| SCHEMBL14691439 | 0.64 | BCL2L1 (0.40) | DHODHPTGDR2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713868-B1 | Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates | BASF AG (DE) | 2002-01-16 | — | — | EP | claimed |
| EP-0713868-A1 | Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates | American Cyanamid Company (US) | 1996-05-29 | — | — | EP | claimed |
| EP-0713868-B1 | Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates | BASF AG (DE) | 2002-01-16 | — | — | EP | disclosed |
| EP-0713868-A1 | Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates | American Cyanamid Company (US) | 1996-05-29 | — | — | EP | disclosed |