Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887445 | 0.88 | ADORA3 (0.49) | KDRADORA3STAT3STAT1FLT1 | |
| SCHEMBL8886688 | 0.87 | KDR (0.45) | NPC1RAB9ASMN1; SMN2MEN1LMNA | |
| SCHEMBL7601915 | 0.86 | STAT3 (0.41) | MEN1KMT2AKDRKDM4ESTAT3 | |
| SCHEMBL8885188 | 0.81 | KMT2A (0.46) | NPC1RAB9ASMN1; SMN2KMT2AKDM4E | |
| SCHEMBL8887522 | 0.75 | KDM4E (0.47) | NPC1RAB9ASMN1; SMN2MEN1LMNA | |
| SCHEMBL15598639 | 0.75 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2MEN1LMNA | |
| SCHEMBL5310221 | 0.71 | KDM4E (0.43) | NPC1RAB9ASMN1; SMN2MEN1LMNA | |
| SCHEMBL27850006 | 0.71 | KDM4E (0.38) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL7739087 | 0.69 | KDR (0.69) | NPC1RAB9ASMN1; SMN2LMNAKDR | |
| SCHEMBL21332119 | 0.68 | DHODH (0.46) | NPC1RAB9ASMN1; SMN2LMNAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713868-B1 | Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates | BASF AG (DE) | 2002-01-16 | — | — | EP | claimed |
| US-5631379-A | CYCLIZATION REACTION OF PERFLUOROALKANOYLAMINO NITRILE WITH ACYL HALIDE | AMERICAN CYANAMID COMPANY (US) | 1997-05-20 | — | — | US | claimed |
| EP-0713868-A1 | Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates | American Cyanamid Company (US) | 1996-05-29 | — | — | EP | claimed |
| EP-0713868-B1 | Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates | BASF AG (DE) | 2002-01-16 | — | — | EP | disclosed |
| US-5631379-A | CYCLIZATION REACTION OF PERFLUOROALKANOYLAMINO NITRILE WITH ACYL HALIDE | AMERICAN CYANAMID COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5574175-A | Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates | AMERICAN CYANAMID CO. (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0713868-A1 | Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates | American Cyanamid Company (US) | 1996-05-29 | — | — | EP | disclosed |
| US-5446170-A | Reacting oxazole amine intermediate with halonitrile in presence of base | AMERICAN CYANAMID COMPANY (US) | 1995-08-29 | — | — | US | disclosed |