Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733507 | 0.89 | ALDH1A1 (0.33) | MAPK1ALDH1A1 | |
| SCHEMBL20772230 | 0.89 | KIF11 (0.31) | — | |
| SCHEMBL8123393 | 0.85 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL2766738 | 0.79 | ALDH1A1 (0.41) | KCNN4MAPK1TSHRALDH1A1ALOX15 | |
| SCHEMBL13221175 | 0.79 | ESR1 (0.41) | KCNN4MAPK1TSHRALDH1A1ALOX15 | |
| SCHEMBL7218962 | 0.79 | KCNN4 (0.34) | KCNN4MAPK1TSHRALDH1A1 | |
| SCHEMBL25373363 | 0.77 | — | — | |
| SCHEMBL11143506 | 0.76 | ATM (0.33) | — | |
| SCHEMBL29196149 | 0.75 | MAPT (0.34) | MAPK1TSHRALDH1A1HPGD | |
| SCHEMBL11501301 | 0.74 | CYP2C9 (0.46) | KCNN4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105050598-B | Novel compounds as ERK inhibitors | 默沙东公司 | 2018-04-27 | — | — | CN | disclosed |
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |
| CN-1116425-A | New cephem compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-02-07 | — | — | CN | disclosed |
| EP-0091130-B1 | CEPHALOSPORIN DERIVATIVES, PROCESS FOR PREPARING AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | DAIICHI SEIYAKU CO., LTD. (JP) | 1987-04-08 | — | — | EP | disclosed |