Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721 | 0.75 | ADORA2A (0.41) | PARP1KDM1AMAOAMAOBMBOAT4 | |
| SCHEMBL8739934 | 0.74 | PARP1 (0.46) | PARP1KDM1AMAOAMAOBMBOAT4 | |
| SCHEMBL11511605 | 0.74 | HSPA5 (0.46) | — | |
| Bromide SCHEMBL9391708 | 0.73 | MBOAT4 (0.41) | PARP1KDM1AMAOAMAOBMBOAT4 | |
| SCHEMBL5498 | 0.70 | BRD4 (0.49) | PARP1KDM1AMAOAMAOBMBOAT4 | |
| SCHEMBL30401571 | 0.67 | NOS2 (0.41) | PARP1KDM1AMAOAMAOBMBOAT4 | |
| SCHEMBL1249740 | 0.67 | NOS2 (0.41) | PARP1KDM1AMAOAMAOBMBOAT4 | |
| SCHEMBL29811249 | 0.67 | — | — | |
| SCHEMBL105003 | 0.67 | — | — | |
| SCHEMBL17656042 | 0.65 | MBOAT4 (0.44) | PARP1KDM1AMAOAMAOBMBOAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631264-A | NEUROLOGICAL DISORDERS | SANOFI WINTHROP, INC. (US) | 1997-05-20 | — | — | US | disclosed |