Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | PNP | P00491 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EDNRA | P25101 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | VCP | P55072 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22021887 | 0.82 | MEN1 (0.51) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL18769787 | 0.82 | MEN1 (0.51) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL5021598 | 0.78 | XDH (0.55) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL8905863 | 0.78 | PNP (0.51) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL21090694 | 0.78 | MEN1 (0.47) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL21417341 | 0.77 | XDH (0.53) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL22704545 | 0.77 | MEN1 (0.49) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL22260577 | 0.77 | MEN1 (0.49) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL20610967 | 0.75 | MEN1 (0.44) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL11091666 | 0.75 | XDH (0.49) | TK1BLMPNPUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663175-A | THYMIDINE KINASE | MERCK & CO. INC. (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0055239-A1 | Novel derivatives of guanine | Astra Läkemedel Aktiebolag (SE) | 1982-06-30 | — | — | EP | disclosed |