Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | VCP | P55072 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HBB | P68871 | 2/20 | 0.47 |
| ▸ | PNP | P00491 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827038 | 0.81 | BLM (0.52) | XDHMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL8905863 | 0.81 | PNP (0.51) | XDHMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL28789611 | 0.79 | XDH (0.47) | XDHMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL5021598 | 0.78 | XDH (0.55) | XDHMEN1KMT2ABLMHBB | |
| SCHEMBL9828669 | 0.78 | MEN1 (0.49) | XDHMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL21417341 | 0.77 | XDH (0.53) | XDHMEN1KMT2ABLMHBB | |
| SCHEMBL8887755 | 0.75 | TK1 (0.52) | XDHMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL28591909 | 0.74 | MEN1 (0.47) | XDHMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL22021887 | 0.74 | MEN1 (0.51) | XDHMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL21539869 | 0.74 | XDH (0.50) | XDHMEN1KMT2ABLMHBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105486-A2 | 1-Monophosphate esters, 1,3-bisphosphate esters and cyclic phosphate esters of 9-(1,3-dihydroxy-2-propoxymethyl)-guanine as antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1984-04-18 | — | — | EP | disclosed |