Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888198 | 0.85 | KMT2A (0.52) | KMT2AALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL8887242 | 0.76 | ALDH1A1 (0.59) | KMT2AALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL11623111 | 0.75 | ALDH1A1 (0.57) | KMT2AALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL5682853 | 0.75 | KMT2A (0.61) | KMT2AALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL11622464 | 0.75 | ALDH1A1 (0.54) | KMT2AALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL8888165 | 0.74 | ALDH1A1 (0.56) | KMT2AALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL8886566 | 0.74 | ALDH1A1 (0.56) | KMT2AALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL18394312 | 0.73 | ALDH1A1 (0.49) | KMT2AALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL19068409 | 0.73 | ALDH1A1 (0.55) | KMT2AALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL5686135 | 0.73 | KMT2A (0.58) | KMT2AALDH1A1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602277-A | Substituted benzene derivatives useful as neuraminidase inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996030329-A1 | SUBSTITUTED BENZENE DERIVATIVES USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INCORPORATED (US) | 1996-10-03 | — | — | WO | disclosed |