Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887771 | 0.85 | KMT2A (0.48) | KMT2AALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL8888165 | 0.83 | ALDH1A1 (0.56) | KMT2AALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL3530705 | 0.82 | ALDH1A1 (0.47) | ALDH1A1NPC1KDM4EMAPTHSD17B10 | |
| SCHEMBL8887242 | 0.80 | ALDH1A1 (0.59) | KMT2AALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL2329286 | 0.79 | NPC1 (0.46) | ALDH1A1NPC1KDM4EMAPTHSD17B10 | |
| SCHEMBL11623111 | 0.79 | ALDH1A1 (0.57) | KMT2AALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL5682853 | 0.78 | KMT2A (0.61) | KMT2AALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL11622464 | 0.78 | ALDH1A1 (0.54) | KMT2AALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL8886566 | 0.78 | ALDH1A1 (0.56) | KMT2AALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL28895911 | 0.77 | SMN1; SMN2 (0.62) | KMT2AALDH1A1SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602277-A | Substituted benzene derivatives useful as neuraminidase inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996030329-A1 | SUBSTITUTED BENZENE DERIVATIVES USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INCORPORATED (US) | 1996-10-03 | — | — | WO | disclosed |