Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 2/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197845 | 0.81 | RPS6KB1 (0.40) | RPS6KB1ADH1BADH1CADH1AADH4 | |
| SCHEMBL8888022 | 0.78 | SMN1; SMN2 (0.49) | CCR4SRCKDM4EMEN1NPC1 | |
| SCHEMBL8596772 | 0.76 | RPS6KB1 (0.39) | RPS6KB1IDO1ADH1BADH1CADH1A | |
| SCHEMBL8886903 | 0.70 | IDO1 (0.39) | RPS6KB1IDO1ADH1BADH1CADH1A | |
| SCHEMBL9383738 | 0.69 | DYRK3 (0.47) | RPS6KB1EGFRKDM4ERAB9ACDK1 | |
| SCHEMBL20652469 | 0.67 | STK17A (0.36) | RPS6KB1CCR4IDO1ADH1BADH1C | |
| SCHEMBL19464345 | 0.64 | L3MBTL1 (0.55) | IDO1KDM4EMEN1NPC1RAB9A | |
| SCHEMBL20746952 | 0.64 | KMT2A (0.46) | IDO1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL8856312 | 0.64 | PRSS1 (0.33) | KDM4EMEN1KMT2ALMNATLR8 | |
| SCHEMBL22000398 | 0.63 | SMN1; SMN2 (0.47) | CCR4ADH1BADH1CADH1AADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668140-A | INSECTICIDE, ACARICIDE, NEMATOCIDE, FUNGICIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-16 | — | — | US | disclosed |
| EP-0519211-A1 | Substituted 4-aminopyrimidine, process for their preparation and their use as parasiticide | Hoechst Schering AgrEvo GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |