Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | DNM2 | P50570 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886910 | 0.77 | DNM2 (0.60) | DNM2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL12411077 | 0.75 | NPC1 (0.44) | KDM4ENPC1RAB9AMAPTNFKB1 | |
| SCHEMBL25065157 | 0.72 | HTR2A (0.33) | CYP2C19FLT3TYRO3MERTKGAS6 | |
| SCHEMBL8596772 | 0.70 | RPS6KB1 (0.39) | IDO1ADH1BADH1CADH1AADH4 | |
| SCHEMBL8888015 | 0.70 | RPS6KB1 (0.39) | IDO1KDM4ENPC1RAB9AADH1B | |
| SCHEMBL3884081 | 0.69 | PDGFRB (0.47) | IDO1MAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL8346152 | 0.69 | CYP2C19 (0.44) | KDM4ENPC1RAB9AMAPTNFKB1 | |
| SCHEMBL23219792 | 0.67 | IDO1 (0.44) | IDO1KDM4ECYP2C19ALDH1A1ADRB2 | |
| SCHEMBL13600415 | 0.66 | NPC1 (0.47) | KDM4ENPC1RAB9AMAPTNFKB1 | |
| SCHEMBL19464345 | 0.66 | L3MBTL1 (0.55) | IDO1KDM4ENPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668140-A | INSECTICIDE, ACARICIDE, NEMATOCIDE, FUNGICIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-16 | — | — | US | disclosed |
| EP-0519211-A1 | Substituted 4-aminopyrimidine, process for their preparation and their use as parasiticide | Hoechst Schering AgrEvo GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |