Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900127 | 0.91 | SMN1; SMN2 (0.55) | ALDH1A1NPC1SMN1; SMN2KDM4EGAA | |
| SCHEMBL132773 | 0.84 | ALDH1A1 (0.78) | ALDH1A1KDM4EMAPK1HSD17B10CA2 | |
| SCHEMBL10989390 | 0.84 | PTPN11 (0.49) | ALDH1A1NPC1SMN1; SMN2KDM4EGAA | |
| SCHEMBL23771906 | 0.84 | SMN1; SMN2 (0.71) | ALDH1A1NPC1SMN1; SMN2KDM4EGAA | |
| SCHEMBL6665051 | 0.84 | CA12 (0.65) | ALDH1A1NPC1SMN1; SMN2KDM4EGAA | |
| SCHEMBL14205555 | 0.84 | ALDH1A1 (0.56) | ALDH1A1NPC1SMN1; SMN2KDM4EGAA | |
| SCHEMBL8823933 | 0.84 | NPC1 (0.62) | ALDH1A1NPC1SMN1; SMN2KDM4EGAA | |
| SCHEMBL13329101 | 0.83 | SMN1; SMN2 (0.57) | ALDH1A1NPC1SMN1; SMN2KDM4EGAA | |
| SCHEMBL20963533 | 0.82 | NPC1 (0.50) | ALDH1A1NPC1SMN1; SMN2KDM4EGAA | |
| SCHEMBL7110777 | 0.82 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024123929-A1 | DEVELOPMENT OF POTENT DUAL HDAC/BRD4 INHIBITORS | BIOVENTURES, LLC (US) | 2024-06-13 | — | — | WO | disclosed |
| EP-1084137-B1 | PEPTIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-02-18 | — | — | EP | disclosed |
| US-20070213283-A1 | Macrolides substituted at the 4\"-position | GLAXO GROUP LIMITED (GB) | 2007-09-13 | — | — | US | disclosed |
| US-20070213283-A1 | Macrolides substituted at the 4\"-position | GLAXO GROUP LIMITED (GB) | 2007-09-13 | — | — | US | disclosed |
| US-5614486-A | DIETHYL 1,4-CYCLOHEXANEDICARBOXYLATE | FIRMENICH SA (CH) | 1997-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213283-A1 | Macrolides substituted at the 4\"-position | IL4, CYP51A1, IL17A | ALDH1A1 2288/4885NPC1 129/4885SMN1; SMN2 1956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.