Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SPOP | O43791 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10426591 | 0.80 | MEN1 (0.50) | ELANETDP1KDM4ETSHRHSD17B10 | |
| SCHEMBL9353469 | 0.80 | MEN1 (0.50) | ELANETDP1KDM4ETSHRHSD17B10 | |
| SCHEMBL9349269 | 0.80 | MEN1 (0.50) | ELANETDP1KDM4ETSHRHSD17B10 | |
| SCHEMBL9617893 | 0.80 | MEN1 (0.50) | ELANETDP1KDM4ETSHRHSD17B10 | |
| SCHEMBL9349167 | 0.79 | MEN1 (0.49) | ELANETDP1KDM4ETSHRHSD17B10 | |
| SCHEMBL8889147 | 0.77 | ELANE (0.46) | ELANEKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL8806354 | 0.76 | ELANE (0.40) | ELANETDP1PTGS1 | |
| SCHEMBL8809929 | 0.75 | ELANE (0.38) | ELANETDP1KDM4ETSHRHSD17B10 | |
| SCHEMBL11177496 | 0.72 | ELANE (0.49) | ELANETDP1KDM4ETSHRHSD17B10 | |
| SCHEMBL11564730 | 0.72 | ELANE (0.49) | ELANETDP1KDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003042-A1 | 6-ETHYLIDENE PENEM DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1993-02-18 | — | — | WO | disclosed |