Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 9/20 | 0.69 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | OGG1 | O15527 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8911047 | 0.99 | MERTK (0.68) | MERTKNPY5RHTTSMN1; SMN2NPC1 | |
| SCHEMBL8889650 | 0.88 | MERTK (0.76) | MERTKNPY5RHTTSMN1; SMN2NPC1 | |
| SCHEMBL30896198 | 0.88 | MERTK (0.76) | MERTKNPY5RHTTSMN1; SMN2NPC1 | |
| SCHEMBL8891059 | 0.87 | MERTK (0.66) | MERTKNPY5RHTTSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL8891541 | 0.87 | MERTK (0.74) | MERTKNPY5RHTTSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL8909111 | 0.87 | MERTK (0.64) | MERTKNPY5RHTTSMN1; SMN2NPC1 | |
| SCHEMBL8890752 | 0.86 | MERTK (0.69) | MERTKNPY5RHTTSMN1; SMN2MAPT | |
| SCHEMBL8890749 | 0.85 | MERTK (0.62) | MERTKNPY5RHTTSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL8900421 | 0.84 | MERTK (0.61) | MERTKNPY5RHTTSMN1; SMN2NPC1 | |
| SCHEMBL27223954 | 0.84 | MERTK (0.60) | MERTKNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |